Microbial Keratitis

Good resources, poached from Yanoff’s Ophthalmology

Yanoff Ophthalmology

O’Brien TP, Maguire MG, Fink NE, et al. Efficacy of ofloxacin vs cefazolin and tobramycin in the therapy for bacterial keratitis. Report from the Bacterial Keratitis Study Research Group. Arch Ophthalmol. 1995;113:1257–1265.

Srinivasan M, Mascarenhas J, Rajaraman R, et al. Corticosteroids for bacterial keratitis: the Steroids for Corneal Ulcers Trial (SCUT). Arch Ophthalmol. 2012;130:143–150.

Dalmon C, Porco TC, Lietman TM, et al. The clinical differentiation of bacterial and fungal keratitis: A photographic survey. Invest Ophthalmol Vis Sci. 2012;53:1787-1791.

• in this study, 15 corneal specialists were only able to distinguish between bacterial and fungal keratitis in aroud 70% of the time. this shows the importance of getting a scrape. 70% seems pretty good, but not perfect.

Labetoulle M, Frau E, Offret H, et al. Non-preserved 1% lidocaine solution has less antibacterial properties than currently available anaesthetic eye-drops. Curr Eye Res. 2002;25:91-97. - apparently this study showed that topical anaesthetic decreases bacterial yield

cite the AAO PPP for the following table: